Biography

Shobha Dagamajalu

Ph.D.

Associate Professor

Dr. Shobha D is currently engaged in the molecularization of traditional medicines and Ayurvedic formulations with anticancer potential, employing proteomics and metabolomics approaches to facilitate their development into effective cancer therapeutics. Her research also focuses on drug repurposing of FDA-approved non-oncology drugs for cancer therapy by identifying cancer-associated kinases through phosphoproteomics and metabolomics analyses. In addition, she is involved in the development and curation of comprehensive signaling pathway maps related to cardiovascular diseases, cancer, and infectious diseases. These integrative pathway resources aid in identifying key molecular regulators, novel therapeutic targets, and network-level interactions, thereby supporting rational drug design and systems-level understanding of disease mechanisms.

Research Area /Interest

Proteomics and Metabolomics, Post-translational modifications in cancer, Molecular targets of traditional / Ayurvedic medicine, Drug repurposing in cancer, Metabolomics of human diseases and traditional medicines.

Ashwini Prabhu, Shobha Dagamajalu, Suchitha GP, Pavan SR, TS Keshava Prasad. Formulation for inhibiting colorectal cancer. 13th November, 2024, Patent No: 202441087590.

Publications

Rai AB, Kandel CA, Bhat S, Ammankallu S, Parate SS, Upadhyay SS, et al. The network map of nesfatin-1-mediated signaling pathway in physiological regulation and pathological conditions. Expert Review of Proteomics; 2026. In press.

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