Center for Systems Biology and Molecular Medicine

An ICMR collaborating centre of excellence (ICMR-CCoE)

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Biography

T. S. Keshava Prasad

Ph.D.

Professor and Deputy Director

Publications

1.

Arefian M, Prasad TS. Susceptibility of rice crop to salt threat: proteomic, metabolomic, and physiological inspections. Journal of Proteome Research. 2022;

[DOI]


2.

Ramesh P, Bajire SK, Kanichery A, Najar MA, Shastry RP, Prasad TK. 6-Methylcoumarin rescues bacterial quorum sensing induced ribosome-inactivating stress in Caenorhabditis elegans. Microbial Pathogenesis. 2022;

[DOI]


3.

Anusha-Kiran Y, Mol P, Dey G, Bhat FA, Chatterjee O, Deolankar SC, Philip M, Prasad TK, Bharath MS, Mahadevan A. Regional heterogeneity in mitochondrial function underlies region specific vulnerability in human brain ageing: Implications for neurodegeneration. Free Radical Biology and Medicine. 2022;

[DOI]


4.

Najar MA, Arefian M, Sidransky D, Gowda H, Prasad TK, Modi PK, Chatterjee A. Tyrosine phosphorylation profiling revealed the signaling network characteristics of CAMKK2 in gastric adenocarcinoma. Frontiers in Genetics. 2022;

[DOI]


5.

Nizamuddin A, Ramesha KP, Rana E, Kasargod S, Behera SK, Ashokan M, Patil AH, Jeyakumar S, Kumaresan A, Kataktalware MA, Das DN. Transcriptomic analysis of PBMCs reveals COX3, BCL2, ATP2B4, B4GALT1, LACTB, FASN and CSN family genes regulating milk performance in lactating Bos indicus cows of Southern India.

[DOI]


6.

Gopalakrishnan L, Chatterjee O, Ravishankar N, Suresh S, Raju R, Mahadevan A, Prasad TK. Opioid receptors signaling network. Journal of Cell Communication and Signaling. 2022;

[DOI]


7.

Kumari G, Rex DA, Goswami S, Mukherjee S, Biswas S, Maurya P, Jain R, Garg S, Prasad TS, Pati S, Ramalingam S. Dynamic palmitoylation of red cell membrane proteins governs susceptibility to invasion by the malaria parasite, Plasmodium falciparum. ACS Infectious Diseases. 2022;

[DOI]


8.

Mol P, Gopalakrishnan L, Chatterjee O, Mangalaparthi KK, Kumar M, Durgad SS, Nair B, Shankar SK, Mahadevan A, Prasad TS. Proteomic analysis of adult human hippocampal Subfields demonstrates Regional Heterogeneity in the protein expression. Journal of Proteome Research. 2022 Aug 30;21(10):2293-310.

[DOI]


9.

Anam Z, Kumari G, Mukherjee S, Rex DA, Biswas S, Maurya P, Ravikumar S, Gupta N, Kushawaha AK, Sah RK, Chaurasiya A. Complementary crosstalk between palmitoylation and phosphorylation events in MTIP regulates its role during Plasmodium falciparum invasion. Frontiers in Cellular and Infection Microbiology. 2022;

[DOI]


10.

Rex DA, Keshava Prasad TS, Kandasamy RK. Revisiting regulated cell death responses in viral infections. International journal of molecular sciences. 2022;

[DOI]


11.

Subba P, Prasad TS. Scope of Proteogenomic Analysis for Indian Sandalwood (Santalum Album). InThe Sandalwood Genome 2022 Mar 1 (pp. 89-97). Cham: Springer International Publishing.

[DOI]


12.

Kasaragod S, Kotimoole CN, Gurtoo S, Prasad TS, Gowda H, Modi PK. A computational workflow for predicting cancer neo-antigens. Bioinformation. 2022;

[DOI]


13.

Shah SR, Mohanty V, Chaudhury D, Prasad TK, Shenoy MM. Evaluation of serum proteome from Indian psoriasis patients. Bioinformation. 2022;

[DOI]


14.

Mol P, Chatterjee O, Gopalakrishnan L, Mangalaparthi KK, Bhat F, Kumar M, Nair B, Shankar SK, Mahadevan A, Prasad TS. Age-associated molecular changes in human Hippocampus subfields as determined by quantitative proteomics. OMICS: A Journal of Integrative Biology. 2022;

[DOI]


15.

Yelamanchi SD, Mishra A, Behra SK, Karthikkeyan G, Keshava Prasad TS, Surolia A. Rifampicin-mediated metabolic changes in Mycobacterium tuberculosis. Metabolites. 2022;

[DOI]


16. Arefian M, Antil N, Najar MA, Subba P, Prasad TK. Phosphoproteome profiling of rice tissues provides new insights into responsive mechanisms and kinase activity upon salt stress. Environmental and Experimental Botany. 2022; [DOI]


17.

Phukan H, Sarma A, Rex DA, Rai AB, Prasad TS, Madanan MG. Unique posttranslational modification sites of acetylation, citrullination, glutarylation, and phosphorylation are found to be specific to the proteins partitioned in the Triton X-114 fractions of Leptospira. ACS omega. 2022;

[DOI]


18.

Thimmappa PY, Nair AS, Najar MA, Mohanty V, Shastry S, Prasad TS, Joshi MB. Quantitative phosphoproteomics reveals diverse stimuli activate distinct signaling pathways during neutrophil activation. Cell and tissue research. 2022;

[DOI]


19.

Antil N, Arefian M, Kandiyil MK, Awasthi K, Prasad TS, Raju R. The core human microRNAs regulated by Toxoplasma gondii. MicroRNA. 2022;

[DOI]


20.

Saptami K, Arokia Balaya Rex D, Chandrasekaran J, Rekha PD. Competitive interaction of thymol with cviR inhibits quorum sensing and associated biofilm formation in Chromobacterium violaceum. International Microbiology. 2022;

[DOI]


21.

Rex DA, Vaid N, Deepak K, Dagamajalu S, Prasad TK. A comprehensive review on current understanding of bradykinin in COVID-19 and inflammatory diseases. Molecular biology reports. 2022;

[DOI]


22.

Venugopal G, Gangaraj KP, Muralikrishna KS, Prasad TK, Rajesh MK. Transcriptome assembly of coconut endosperm callus (Laccadive Micro Tall cv.) and its functional annotation.

[DOI]


23. Subba P, Saha P, Karthikkeyan G, Biswas M, Prasad TS, Roy‐Barman S. Metabolite profiling reveals overexpression of the global regulator, MoLAEA leads to increased synthesis of metabolites in Magnaporthe oryzae. Journal of Applied Microbiology. 2022; [DOI]


24.

Nekrakalaya B, Arefian M, Kotimoole CN, Krishna RM, Palliyath GK, Najar MA, Behera SK, Kasaragod S, Santhappan P, Hegde V, Prasad TS. Towards phytopathogen diagnostics? Coconut bud rot pathogen Phytophthora palmivora mycelial proteome analysis informs genome annotation. OMICS: A Journal of Integrative Biology. 2022;

[DOI]


25.

Rex DA, Patil AH, Modi PK, Kandiyil MK, Kasaragod S, Pinto SM, Tanneru N, Sijwali PS, Prasad TS. Dissecting Plasmodium yoelii pathobiology: proteomic approaches for decoding novel translational and post-translational modifications. ACS omega. 2022;

[DOI]


26.

Rex DA, Suchitha GP, Palollathil A, Kanichery A, Prasad TK, Dagamajalu S. The network map of urotensin-II mediated signaling pathway in physiological and pathological conditions. Journal of Cell Communication and Signaling. 2022;

[DOI]


27.

Yelamanchi SD, Arun Kumar ST, Mishra A, Keshava Prasad TS, Surolia A. Metabolite dysregulation by pranlukast in Mycobacterium tuberculosis. Molecules. 2022;

[DOI]


28.

Dagamajalu S, Rex DA, Suchitha GP, Rai AB, Rainey JK, Prasad TK. The network map of Elabela signaling pathway in physiological and pathological conditions. Journal of Cell Communication and Signaling. 2022;

[DOI]


29.

Revikumar A, Kashyap V, Palollathil A, Aravind A, Raguraman R, Kumar KM, Vijayakumar M, Prasad TS, Raju R. Multiple G-quadruplex binding ligand induced transcriptomic map of cancer cell lines. Journal of Cell Communication and Signaling. 2022;

[DOI]


30.

Dagamajalu S, Rex DA, Philem PD, Rainey JK, Keshava Prasad TS. A network map of apelin-mediated signaling. Journal of Cell Communication and Signaling. 2022;

[DOI]


31.

Maurya R, Tripathi A, Kumar M, Antil N, Yamaryo‐Botté Y, Kumar P, Bansal P, Doerig C, Botté CY, Prasad TK, Sharma P. PI4‐kinase and PfCDPK7 signaling regulate phospholipid biosynthesis in Plasmodium falciparum. EMBO reports. 2022;

[DOI]


32.

DasGupta M, Kumaresan A, Saraf KK, Paul N, Sajeevkumar T, Karthikkeyan G, Prasad TK, Modi PK, Ramesha K, Manimaran A, Jeyakumar S. Deciphering metabolomic alterations in seminal plasma of crossbred (Bos taurus X Bos indicus) bulls through comparative deep metabolomic analysis. Andrologia. 2022;

[DOI]


33.

Awasthi K, Kootimole CN, Aravind A, Prasad TS. Data-independent acquisition approach to proteome: A case study and a spectral library for mass spectrometry-based investigation of mycobacterium tuberculosis. OMICS: A Journal of Integrative Biology. 2022;

[DOI]


34.

Arefian M, Antil N, Najar MA, Behera SK, Subba P, Prasad TS. Identifying novel genes and proteins involved in salt stress perception and signaling of rice seedlings. OMICS: A Journal of Integrative Biology. 2022;

[DOI]


35. Rex DA, Subbannayya Y, Modi PK, Palollathil A, Gopalakrishnan L, Bhandary YP, Prasad TS, Pinto SM. Temporal quantitative phosphoproteomics profiling of interleukin-33 signaling network reveals unique modulators of monocyte activation. Cells. 2022; [DOI]


36.

Rex DA, Deepak K, Vaid N, Dagamajalu S, Kandasamy RK, Flo TH, Keshava Prasad TS. A modular map of Bradykinin-mediated inflammatory signaling network. Journal of cell communication and signaling. 2022;

[DOI]


37.

Aravind A, Palollathil A, Rex DA, Kumar KM, Vijayakumar M, Shetty R, Codi JA, Prasad TS, Raju R. A multi-cellular molecular signaling and functional network map of C–C motif chemokine ligand 18 (CCL18): a chemokine with immunosuppressive and pro-tumor functions. Journal of cell communication and signaling. 2022;

[DOI]


38.

Dasgupta M, Kumaresan A, Saraf KK, Nag P, Sinha MK, Aslam MK M, Karthikkeyan G, Prasad TK, Modi PK, Datta TK, Ramesha K. Deep metabolomic profiling reveals alterations in fatty acid synthesis and ketone body degradations in spermatozoa and seminal plasma of astheno-oligozoospermic bulls. Frontiers in Veterinary Science. 2022;

[DOI]


39.

Rex DA, Subbannayya Y, Modi PK, Palollathil A, Gopalakrishnan L, Bhandary YP, Prasad TS, Pinto SM. Temporal quantitative phosphoproteomics profiling of interleukin-33 signaling network reveals unique modulators of monocyte activation. Cells. 2022;

[DOI]


40.

Arefian M, Antil N, Najar MA, Behera SK, Subba P, Prasad TS. Identifying novel genes and proteins involved in salt stress perception and signaling of rice seedlings. OMICS: A Journal of Integrative Biology. 2022;

[DOI]


41.

Awasthi K, Kootimole CN, Aravind A, Prasad TS. Data-independent acquisition approach to proteome: A case study and a spectral library for mass spectrometry-based investigation of mycobacterium tuberculosis. OMICS: A Journal of Integrative Biology. 2022;

[DOI]


42.

Subba P, Prasad TS. Scope of Proteogenomic Analysis for Indian Sandalwood (Santalum Album). InThe Sandalwood Genome 2022 Mar 1 (pp. 89-97). Cham: Springer International Publishing.

[DOI]


43.

Dasgupta M, Kumaresan A, Saraf KK, Nag P, Sinha MK, Aslam MK M, Karthikkeyan G, Prasad TK, Modi PK, Datta TK, Ramesha K. Deep metabolomic profiling reveals alterations in fatty acid synthesis and ketone body degradations in spermatozoa and seminal plasma of astheno-oligozoospermic bulls. Frontiers in Veterinary Science. 2022;

[DOI]


44. Maurya R, Tripathi A, Kumar M, Antil N, Yamaryo‐Botté Y, Kumar P, Bansal P, Doerig C, Botté CY, Prasad TK, Sharma P. PI4‐kinase and PfCDPK7 signaling regulate phospholipid biosynthesis in Plasmodium falciparum. EMBO reports. 2022; [DOI]


45. Gopalakrishnan L, Chatterjee O, Ravishankar N, Suresh S, Raju R, Mahadevan A, Prasad TK. Opioid receptors signaling network. Journal of Cell Communication and Signaling. 2022; [DOI]


46.

Rex DA, Deepak K, Vaid N, Dagamajalu S, Kandasamy RK, Flo TH, Keshava Prasad TS. A modular map of Bradykinin-mediated inflammatory signaling network. Journal of cell communication and signaling. 2022;

[DOI]


47.

DasGupta M, Kumaresan A, Saraf KK, Paul N, Sajeevkumar T, Karthikkeyan G, Prasad TK, Modi PK, Ramesha K, Manimaran A, Jeyakumar S. Deciphering metabolomic alterations in seminal plasma of crossbred (Bos taurus X Bos indicus) bulls through comparative deep metabolomic analysis. Andrologia. 2022;

[DOI]


48.

Dagamajalu S, Rex DA, Suchitha GP, Rai AB, Rainey JK, Prasad TK. The network map of Elabela signaling pathway in physiological and pathological conditions. Journal of Cell Communication and Signaling. 2022;

[DOI]


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