Center for Systems Biology and Molecular Medicine

An ICMR collaborating centre of excellence (ICMR-CCoE)

img img

Biography

Prashant Kumar Modi

Ph.D.

Associate Professor

Dr. Prashant Kumar Modi obtained his Ph.D. from Banaras Hindu University. During this period he studied the effects of aging on glial cells with special emphasis on the astrocytes of the mice brain. During his post-doctoral training at Dr. Pushkar Sharma‘s laboratory, National Institute of Immunology, New Delhi, he worked on delineating the molecular mechanisms involved in cell cycle related neuronal apoptosis in Alzheimer‘s disease. He has been a recipient of DBT Research Associateship during 2011-2015 from Department of Biotechnology, Govt. of India. Currently, he is involved in the identification of biomarkers and novel therapeutic targets in neurodegenerative diseases such as Parkinson‘s disease and Alzheimer‘s disease using cutting-edge technologies in genomics, proteomics and metabolomics.

 

 

 




Publications

1.

Singh I, Anagha A, Kotimoole CN, Modi PK, Prasad TSK, Hoti SL. Unpacking immune modulation as a site of therapeutics innovation for nematode parasite Wuchereria bancrofti. 2024.

[DOI]


2.

Mahin A, Soman SP, Modi PK, Raju R, Keshava Prasad TS, Abhinand CS. Meta-analysis of the serum/plasma proteome identifies significant associations between COVID-19 with Alzheimer’s/Parkinson’s diseases. Journal of neurovirology. 2024;

[DOI]


3.

Kunnath AN, Parker SK, Crasta DN, Kunhiraman JP, Madhvacharya VV, Kumari S, Nayak G, Lakshmi RV, Modi PK, Prasad TS, Kumar A. Metformin augments major cytoplasmic organization except for spindle organization in oocytes cultured under hyperglycemic and hyperlipidemic conditions: An in vitro study. Toxicology and Applied Pharmacology. 2024

[DOI]


4.

Hegde A, Upadhyay SS, Prasad TS, Modi PK. Mass spectrometry–based approaches for the identification of molecular mechanism of action of ayurvedic medicines in Parkinson disease. InAyurvedic Herbal Preparations in Neurological Disorders 2023;

[DOI]


5.

Dasgupta M, Kumaresan A, Saraf KK, Nag P, Sinha MK, Aslam MK M, Karthikkeyan G, Prasad TK, Modi PK, Datta TK, Ramesha K. Deep metabolomic profiling reveals alterations in fatty acid synthesis and ketone body degradations in spermatozoa and seminal plasma of astheno-oligozoospermic bulls. Frontiers in Veterinary Science. 2022;

[DOI]


6.

Behera SK, Modi PK, Karthikkeyan G, Pervaje SK, Pervaje R, Raju R, Prasad TS, Subbannayya Y. From LC-MS/MS metabolomics profiling of Kanchanara Guggulu to molecular docking and dynamics simulation of quercetin pentaacetate with aldose reductase. Bioinformation. 2021;

[DOI]


7.

DasGupta M, Kumaresan A, Saraf KK, Paul N, Sajeevkumar T, Karthikkeyan G, Prasad TK, Modi PK, Ramesha K, Manimaran A, Jeyakumar S. Deciphering metabolomic alterations in seminal plasma of crossbred (Bos taurus X Bos indicus) bulls through comparative deep metabolomic analysis. Andrologia. 2022;

[DOI]


8.

Najar MA, Aravind A, Dagamajalu S, Sidransky D, Ashktorab H, Smoot DT, Gowda H, Prasad TK, Modi PK, Chatterjee A. Hyperactivation of MEK/ERK pathway by Ca2+/calmodulin‐dependent protein kinase kinase 2 promotes cellular proliferation by activating cyclin‐dependent kinases and minichromosome maintenance protein in gastric cancer cells. Molecular Carcinogenesis. 2021;

[DOI]


9.

Kalal BS, Modi PK, Upadhya D, Saha P, Prasad TS, Pai VR. Inhibition of bone morphogenetic proteins signaling suppresses metastasis melanoma: a proteomics approach. American journal of translational research. 2021;

[PubMed]


© Copyright 2025 - All rights reserved.                   Powered by ONTIME Solution